late 14c., from Old French transmutacion "transformation, change, metamorphosis" (12c.), from Late Latin transmutationem (nominative transmutatio) "a change, shift," noun of action from Latin transmutare "change from one condition to another," from trans- "thoroughly" (see trans-) + mutare "to change" (see mutable). A word from alchemy.[transmutation etymology, transmutation origin, 英语词源]