c. 1600 (in "Measure for Measure," with the disparaging sense "making a show of sanctity, affecting an appearance of holiness"), from sanctimony + -ous. The un-ironic, literal sense was used occasionally in English from c. 1600 to c. 1800. Related: Sanctimoniously; sanctimoniousness.[sanctimonious etymology, sanctimonious origin, 英语词源]