1590s, "pertaining to the hypochondria," also "afflicted with melancholy," from French hypocondriaque (16c.), from Medieval Latin hypochondriacus, from Greek hypokhondriakos "pertaining to the upper abdomen," from hypokhondria (see hypochondria). The noun is from 1630s, "melancholy person;" in the modern sense from 1888.[hypochondriac etymology, hypochondriac origin, 英语词源]