transposition of letters in a word so as to form another, 1580s, from French anagramme or Modern Latin anagramma (16c.), both from Greek anagrammatizein "transpose letters," from ana- "up, back" (see ana-) + gramma (genitive grammatos) "letter" (see -gram). Related: Anagrammatical; anagrammatically.[anagram etymology, anagram origin, 英语词源]