"gigantism due to activity of pituitary after normal growth has ceased," 1886, from French acromégalie, from medical Latin acromegalia, from Greek akron "extremity" (see acrid) + megas "great" (fem. megale; see mickle). Said in contemporary literature to have been coined 1885 by French physician Dr. Pierre Marie.[acromegaly etymology, acromegaly origin, 英语词源]