dis-, 不，非，使相反。advantage,有利的。

1. Depression is the third thing that works to my patients' disadvantage.

抑郁是威胁我的病人健康的第三大杀手。

来自柯林斯例句

2. Her ignorance of the area put her at a decided disadvantage.

她对该地区一无所知，这显然对她不利。

来自柯林斯例句

3. A snap election would be to their disadvantage.

提前选举将对他们不利。

来自柯林斯例句

4. The fact that I was a foreigner was a big disadvantage.

我是外国人这事实对我十分不利。

来自《权威词典》

5. But there is a disadvantage to be set against this fact.

尽管事实如此,相比之下,仍有不利之处.

来自《简明英汉词典》