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spite

spite: [13] Spite was adapted from Old French despit ‘scorn, ill will’, which was also borrowed intact as despite [13]. This came from Latin dēspectus, the past participle of dēspicere ‘look down on’ (source of English despise [13]), which was a compound verb formed from the prefix dē- ‘down’ and specere ‘look’ (source of English spectacle, spy, etc). The use of in spite of and despite for ‘notwithstanding’ goes back via an intermediate ‘in defiance of’ to an original ‘in contempt of’.
=> despise, species, spectator, spy